Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Contents

• 1 Interactions
• 2 See also
• 3 References
• 4 External links
• 5 Further reading

Interactions

FZD7 has been shown to interact with DLG4.

www.4yds.com
http://www.4yds.com/fzd7/ http://www.4yds.com/fzd7/encyclopedia.htm http://www.4yds.com/g%c3%b6del%27s_incompleteness_theorem/ http://www.4yds.com/g%c3%b6del%27s ...
www.4yds.com/urllist.txt

---

	New Location:
city:
state/region:
country: